RegulonDB

Name:

ahpCF -> ahpCF_mRNA

Description:

Transcription of transcription unit ahpCF. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

ahpCF - MetJ-SAM -> ahpCF_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	ahpCF	gene
product	ahpCF_mRNA	RNA

Name:

folE-yeiB -> folE-yeiB_mRNA

Description:

Transcription of transcription unit folE-yeiB. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

folE-yeiB - MetJ-SAM -> folE-yeiB_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	folE-yeiB	gene
product	folE-yeiB_mRNA	RNA

Name:

metA -> metA_mRNA

Description:

Transcription of transcription unit metA. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metA - MetJ-SAM -> metA_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metA	gene
product	metA_mRNA	RNA

Name:

metBL -> metBL_mRNA

Description:

Transcription of transcription unit metBL. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metBL - MetJ-SAM -> metBL_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metBL	gene
product	metBL_mRNA	RNA

Name:

metC -> metC_mRNA

Description:

Transcription of transcription unit metC. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metC - MetJ-SAM -> metC_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metC	gene
product	metC_mRNA	RNA

Name:

metE -> metE_mRNA

Description:

Transcription of transcription unit metE. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metE - MetJ-SAM -> metE_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metE	gene
product	metE_mRNA	RNA

Name:

metF -> metF_mRNA

Description:

Transcription of transcription unit metF. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metF - MetJ-SAM -> metF_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metF	gene
product	metF_mRNA	RNA

Name:

metK -> metK_mRNA

Description:

Transcription of transcription unit metK. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metK - MetJ-SAM -> metK_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metK	gene
product	metK_mRNA	RNA

Name:

metNIQ -> metNIQ_mRNA

Description:

Transcription of transcription unit metNIQ. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metNIQ - MetJ-SAM -> metNIQ_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metNIQ	gene
product	metNIQ_mRNA	RNA

Name:

metR -> metR_mRNA

Description:

Transcription of transcription unit metR. Reaction inhibition by MetJ-SAM.

Type:

transcription

Pathway Components:

metR - MetJ-SAM -> metR_mRNA

Components:

Function	Name	Type
inhibitor	MetJ-SAM	complex
reactant	metR	gene
product	metR_mRNA	RNA

Name:

metA_mRNA -> MetA

Description:

Translation of MetA

Type:

translation

Pathway Components:

metA_mRNA -> MetA

Components:

Function	Name	Type
product	MetA	protein
reactant	metA_mRNA	RNA

Name:

homo-ser + suc-coa -> succinyl-homoserine + coenzyme A

Description:

Reaction transforming homo-ser, suc-coa into succinyl-homoserine, coenzyme A

Type:

state transition

Pathway Components:

homo-ser + suc-coa - MetA - SAM - methionine -> succinyl-homoserine + coenzyme A

Components:

Function	Name	Type
catalyzer	MetA	protein
inhibitor	SAM	simple_molecule
product	coenzyme A	simple_molecule
reactant	homo-ser	simple_molecule
inhibitor	methionine	simple_molecule
reactant	suc-coa	simple_molecule
product	succinyl-homoserine	simple_molecule

Name:

metR_mRNA -> MetR

Description:

Translation of MetR

Type:

translation

Pathway Components:

metR_mRNA -> MetR

Components:

Function	Name	Type
product	MetR	protein
reactant	metR_mRNA	RNA

Name:

metK_mRNA -> MetK

Description:

Translation of MetK

Type:

translation

Pathway Components:

metK_mRNA -> MetK

Components:

Function	Name	Type
product	MetK	protein
reactant	metK_mRNA	RNA

Name:

methionine -> diphosphate + phosphate + SAM

Description:

Reaction transforming methionine into diphosphate, phosphate , SAM

Type:

state transition

Pathway Components:

methionine - MetK - SAM -> diphosphate + phosphate + SAM

Components:

Function	Name	Type
catalyzer	MetK	protein
inhibitor	SAM	simple_molecule
product	SAM	simple_molecule
product	diphosphate	simple_molecule
reactant	methionine	simple_molecule
product	phosphate	simple_molecule

Name:

metF_mRNA -> MetF

Description:

Translation of MetF

Type:

translation

Pathway Components:

metF_mRNA -> MetF

Components:

Function	Name	Type
product	MetF	protein
reactant	metF_mRNA	RNA

Name:

methylene-H4PteGlu(n) -> N5-methyl-tetrahydrofolate

Description:

Reaction transforming methylene-H4PteGlu(n) into N5-methyl-tetrahydrofolate

Type:

state transition

Pathway Components:

methylene-H4PteGlu(n) - MetF -> N5-methyl-tetrahydrofolate

Components:

Function	Name	Type
catalyzer	MetF	protein
product	N5-methyl-tetrahydrofolate	simple_molecule
reactant	methylene-H4PteGlu(n)	simple_molecule

Name:

ahpCF_mRNA -> AhpC

Description:

Translation of AhpC

Type:

translation

Pathway Components:

ahpCF_mRNA -> AhpC

Components:

Function	Name	Type
product	AhpC	protein
reactant	ahpCF_mRNA	RNA

Name:

AhpC + AhpF -> AhpC-AhpF

Description:

Reaction transforming AhpC, AhpF into AhpC-AhpF

Type:

state transition

Pathway Components:

AhpC + AhpF -> AhpC-AhpF

Components:

Function	Name	Type
reactant	AhpC	protein
product	AhpC-AhpF	complex
reactant	AhpF	protein

Name:

ROOH -> alcohol

Description:

Reaction transforming ROOH into alcohol

Type:

state transition

Pathway Components:

ROOH - AhpC-AhpF -> alcohol

Components:

Function	Name	Type
catalyzer	AhpC-AhpF	complex
reactant	ROOH	simple_molecule
product	alcohol	simple_molecule

Name:

ahpCF_mRNA -> AhpF

Description:

Translation of AhpF

Type:

translation

Pathway Components:

ahpCF_mRNA -> AhpF

Components:

Function	Name	Type
product	AhpF	protein
reactant	ahpCF_mRNA	RNA

Name:

folE-yeiB_mRNA -> FolE

Description:

Translation of FolE

Type:

translation

Pathway Components:

folE-yeiB_mRNA -> FolE

Components:

Function	Name	Type
product	FolE	protein
reactant	folE-yeiB_mRNA	RNA

Name:

guanosine-triphosphate -> formate + H2NTP

Description:

Reaction transforming guanosine-triphosphate into formate, H2NTP

Type:

state transition

Pathway Components:

guanosine-triphosphate - FolE -> formate + H2NTP

Components:

Function	Name	Type
catalyzer	FolE	protein
product	H2NTP	simple_molecule
product	formate	simple_molecule
reactant	guanosine-triphosphate	simple_molecule

Name:

folE-yeiB_mRNA -> YeiB

Description:

Translation of YeiB

Type:

translation

Pathway Components:

folE-yeiB_mRNA -> YeiB

Components:

Function	Name	Type
product	YeiB	protein
reactant	folE-yeiB_mRNA	RNA

Name:

metC_mRNA -> MetC

Description:

Translation of MetC

Type:

translation

Pathway Components:

metC_mRNA -> MetC

Components:

Function	Name	Type
product	MetC	protein
reactant	metC_mRNA	RNA

Name:

cystathionine -> homo-cys + pyruvate + ammonium

Description:

Reaction transforming cystathionine into homo-cys, pyruvate , ammonium

Type:

state transition

Pathway Components:

cystathionine - MetC - cysteine -> homo-cys + pyruvate + ammonium

Components:

Function	Name	Type
catalyzer	MetC	protein
product	ammonium	simple_molecule
reactant	cystathionine	simple_molecule
inhibitor	cysteine	simple_molecule
product	homo-cys	simple_molecule
product	pyruvate	simple_molecule

Name:

cystathionine -> dehydroalanine + homo-cys

Description:

Reaction transforming cystathionine into dehydroalanine, homo-cys

Type:

state transition

Pathway Components:

cystathionine - MetC -> dehydroalanine + homo-cys

Components:

Function	Name	Type
catalyzer	MetC	protein
reactant	cystathionine	simple_molecule
product	dehydroalanine	simple_molecule
product	homo-cys	simple_molecule

Name:

cysteine -> ammonium + pyruvate + sulfide

Description:

Reaction transforming cysteine into ammonium, pyruvate , sulfide

Type:

state transition

Pathway Components:

cysteine - MetC -> ammonium + pyruvate + sulfide

Components:

Function	Name	Type
catalyzer	MetC	protein
product	ammonium	simple_molecule
reactant	cysteine	simple_molecule
product	pyruvate	simple_molecule
product	sulfide	simple_molecule

Name:

cysteine -> dehydroalanine + sulfide

Description:

Reaction transforming cysteine into dehydroalanine, sulfide

Type:

state transition

Pathway Components:

cysteine - MetC -> dehydroalanine + sulfide

Components:

Function	Name	Type
catalyzer	MetC	protein
reactant	cysteine	simple_molecule
product	dehydroalanine	simple_molecule
product	sulfide	simple_molecule

Name:

metBL_mRNA -> MetB

Description:

Translation of MetB

Type:

translation

Pathway Components:

metBL_mRNA -> MetB

Components:

Function	Name	Type
product	MetB	protein
reactant	metBL_mRNA	RNA

Name:

succinyl-homoserine + cysteine -> cystathionine + succinate

Description:

Reaction transforming succinyl-homoserine, cysteine into cystathionine, succinate

Type:

state transition

Pathway Components:

succinyl-homoserine + cysteine - MetB -> cystathionine + succinate

Components:

Function	Name	Type
catalyzer	MetB	protein
product	cystathionine	simple_molecule
reactant	cysteine	simple_molecule
product	succinate	simple_molecule
reactant	succinyl-homoserine	simple_molecule

Name:

succinyl-homoserine -> 2-oxobutyrate + succinate + ammonium

Description:

Reaction transforming succinyl-homoserine into 2-oxobutyrate, succinate , ammonium

Type:

state transition

Pathway Components:

succinyl-homoserine - MetB -> 2-oxobutyrate + succinate + ammonium

Components:

Function	Name	Type
product	2-oxobutyrate	simple_molecule
catalyzer	MetB	protein
product	ammonium	simple_molecule
product	succinate	simple_molecule
reactant	succinyl-homoserine	simple_molecule

Name:

succinyl-homoserine -> (2Z)-2-aminobut-2-enoate + succinate

Description:

Reaction transforming succinyl-homoserine into (2Z)-2-aminobut-2-enoate, succinate

Type:

state transition

Pathway Components:

succinyl-homoserine - MetB -> (2Z)-2-aminobut-2-enoate + succinate

Components:

Function	Name	Type
product	(2Z)-2-aminobut-2-enoate	simple_molecule
catalyzer	MetB	protein
product	succinate	simple_molecule
reactant	succinyl-homoserine	simple_molecule

Name:

metBL_mRNA -> MetL

Description:

Translation of MetL

Type:

translation

Pathway Components:

metBL_mRNA -> MetL

Components:

Function	Name	Type
product	MetL	protein
reactant	metBL_mRNA	RNA

Name:

aspartate -> aspartyl-4-P

Description:

Reaction transforming aspartate into aspartyl-4-P

Type:

state transition

Pathway Components:

aspartate - MetL - homo-ser -> aspartyl-4-P

Components:

Function	Name	Type
catalyzer	MetL	protein
reactant	aspartate	simple_molecule
product	aspartyl-4-P	simple_molecule
inhibitor	homo-ser	simple_molecule

Name:

aspartate-semialdehyde -> homo-ser

Description:

Reaction transforming aspartate-semialdehyde into homo-ser

Type:

state transition

Pathway Components:

aspartate-semialdehyde - MetL -> homo-ser

Components:

Function	Name	Type
catalyzer	MetL	protein
reactant	aspartate-semialdehyde	simple_molecule
product	homo-ser	simple_molecule

Name:

metNIQ_mRNA -> MetN

Description:

Translation of MetN

Type:

translation

Pathway Components:

metNIQ_mRNA -> MetN

Components:

Function	Name	Type
product	MetN	protein
reactant	metNIQ_mRNA	RNA

Name:

MetQ + MetI + MetN -> MetN-MetI-MetQ

Description:

Reaction transforming MetQ, MetI, MetN into MetN-MetI-MetQ

Type:

state transition

Pathway Components:

MetQ + MetI + MetN -> MetN-MetI-MetQ

Components:

Function	Name	Type
reactant	MetI	protein
reactant	MetN	protein
product	MetN-MetI-MetQ	complex
reactant	MetQ	protein

Name:

methionine_Ext -> methionine

Description:

Transport of methionine_Ext through a bacterial membrane, leading to the presence of methionine inside the cell.

Type:

transport

Pathway Components:

methionine_Ext - MetN-MetI-MetQ -> methionine

Components:

Function	Name	Type
catalyzer	MetN-MetI-MetQ	complex
product	methionine	simple_molecule
reactant	methionine_Ext	simple_molecule

Name:

Methionine S-oxide_Ext -> Methionine S-oxide

Description:

Transport of Methionine S-oxide_Ext through a bacterial membrane, leading to the presence of Methionine S-oxide inside the cell.

Type:

transport

Pathway Components:

Methionine S-oxide_Ext - MetN-MetI-MetQ -> Methionine S-oxide

Components:

Function	Name	Type
catalyzer	MetN-MetI-MetQ	complex
product	Methionine S-oxide	simple_molecule
reactant	Methionine S-oxide_Ext	simple_molecule

Name:

methionine-R-sulfoxide_Ext -> methionine-R-sulfoxide

Description:

Transport of methionine-R-sulfoxide_Ext through a bacterial membrane, leading to the presence of methionine-R-sulfoxide inside the cell.

Type:

transport

Pathway Components:

methionine-R-sulfoxide_Ext - MetN-MetI-MetQ -> methionine-R-sulfoxide

Components:

Function	Name	Type
catalyzer	MetN-MetI-MetQ	complex
product	methionine-R-sulfoxide	simple_molecule
reactant	methionine-R-sulfoxide_Ext	simple_molecule

Name:

methionine-(S)-S-oxide_Ext -> methionine-(S)-S-oxide

Description:

Transport of methionine-(S)-S-oxide_Ext through a bacterial membrane, leading to the presence of methionine-(S)-S-oxide inside the cell.

Type:

transport

Pathway Components:

methionine-(S)-S-oxide_Ext - MetN-MetI-MetQ -> methionine-(S)-S-oxide

Components:

Function	Name	Type
catalyzer	MetN-MetI-MetQ	complex
product	methionine-(S)-S-oxide	simple_molecule
reactant	methionine-(S)-S-oxide_Ext	simple_molecule

Name:

acetyl-DL-methionine_Ext -> acetyl-DL-methionine

Description:

Transport of acetyl-DL-methionine_Ext through a bacterial membrane, leading to the presence of acetyl-DL-methionine inside the cell.

Type:

transport

Pathway Components:

acetyl-DL-methionine_Ext - MetN-MetI-MetQ -> acetyl-DL-methionine

Components:

Function	Name	Type
catalyzer	MetN-MetI-MetQ	complex
product	acetyl-DL-methionine	simple_molecule
reactant	acetyl-DL-methionine_Ext	simple_molecule

Name:

metNIQ_mRNA -> MetI

Description:

Translation of MetI

Type:

translation

Pathway Components:

metNIQ_mRNA -> MetI

Components:

Function	Name	Type
product	MetI	protein
reactant	metNIQ_mRNA	RNA

Name:

metNIQ_mRNA -> MetQ

Description:

Translation of MetQ

Type:

translation

Pathway Components:

metNIQ_mRNA -> MetQ

Components:

Function	Name	Type
product	MetQ	protein
reactant	metNIQ_mRNA	RNA

Name:

metE_mRNA -> MetE

Description:

Translation of MetE

Type:

translation

Pathway Components:

metE_mRNA -> MetE

Components:

Function	Name	Type
product	MetE	protein
reactant	metE_mRNA	RNA

Name:

5-methyltetrahydropteroyl tri-L-glutamate + homo-cys -> H4PteGlu(n) + methionine

Description:

Reaction transforming 5-methyltetrahydropteroyl tri-L-glutamate, homo-cys into H4PteGlu(n), methionine

Type:

state transition

Pathway Components:

5-methyltetrahydropteroyl tri-L-glutamate + homo-cys - MetE -> H4PteGlu(n) + methionine

Components:

Function	Name	Type
reactant	5-methyltetrahydropteroyl tri-L-glutamate	simple_molecule
product	H4PteGlu(n)	simple_molecule
catalyzer	MetE	protein
reactant	homo-cys	simple_molecule
product	methionine	simple_molecule

Name:

homo-cys -> methionine

Description:

Transformation of homo-cys into methionine by one or more reactions not shown.

Type:

complementary pathway reaction

Pathway Components:

homo-cys / HOMOCYSMETB12-RXN / methionine

Components:

Function	Name	Type
reactant	homo-cys	simple_molecule
product	methionine	simple_molecule

Name:

SAM -> homo-cys

Description:

Transformation of SAM into homo-cys by one or more reactions not shown.

Type:

complementary pathway reaction

Pathway Components:

SAM / RXN-7605 / ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN / RIBOSYLHOMOCYSTEINASE-RXN / homo-cys

Components:

Function	Name	Type
reactant	SAM	simple_molecule
product	homo-cys	simple_molecule

Name:

aspartyl-4-P -> aspartate-semialdehyde

Description:

Transformation of aspartyl-4-P into aspartate-semialdehyde by one or more reactions not shown.

Type:

complementary pathway reaction

Pathway Components:

aspartyl-4-P / ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN / aspartate-semialdehyde

Components:

Function	Name	Type
product	aspartate-semialdehyde	simple_molecule
reactant	aspartyl-4-P	simple_molecule

Gensor Unit Map