RegulonDB RegulonDB 11.2: Operon Form
   

mgtS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mgtS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: mgtS
Gene(s): mgtS   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
[EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
[EXP-IDA-TRANSCRIPT-LEN-DETERMINATION] Length of transcript experimentally determined
Reference(s): [1] Moon K., et al., 2009
Promoter
Name: mgtSp
+1: 1622588
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 58
Sequence: gaacacaataaagatttaattcagccttcgtttaggttacctctgctaatatctttctcaTtgagatgaaaattaaggtaa
                    -35                        -10          +1                   
Evidence: [COMP-AINF]
[COMP-HINF]
[EXP-IDA-TRANSCRIPTION-INIT-MAPPING]
Reference(s): [2] Huerta AM., et al., 2003
[1] Moon K., et al., 2009
Terminator(s)
Type: rho-independent
Sequence: ccctcacctaACCGGCCCCTTGTTACAGTTGTGTACAAGGGGCCtgatttttat
Reference(s): [1] Moon K., et al., 2009
TF binding sites (TFBSs)
[PhoP,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PhoP-phosphorylated activator mgtSp 1622545 1622561 -35.0 ataaagatttAATTCAGCCTTCGTTTAggttacctct nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [COMP-HINF-SIMILAR-TO-CONSENSUS] W [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-HINF] Inferred by a human based on computational evidence

 [EXP-IDA-TRANSCRIPTION-INIT-MAPPING] Transcription initiation mapping

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [COMP-HINF-SIMILAR-TO-CONSENSUS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.


Reference(s)    

 [1] Moon K., Gottesman S., 2009, A PhoQ/P-regulated small RNA regulates sensitivity of Escherichia coli to antimicrobial peptides., Mol Microbiol 74(6):1314-30

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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